Top Quality, Best Price, Chinese Supplier Antibiotic Agent API Kanamycin Sulfate

Top Quality, Best Price, Chinese Supplier Antibiotic Agent API Kanamycin Sulfate

Kanamycin is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.

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Product Details

Chemical & Physical Properties:

CAS NO: 70560-51-9

Molecular Formular: C18H38N4O15S

MW:582.58

Melting point: 250°C

EINECS: 246-933-9

RTECS: NZ3225030

Storage temp.: 0-6°C

Items

Specification

Description

White to Off white powder

PH

7.0~9.0

Loss on drying

3%

Boiling point

943.2°C at 760 mmHg

Assay

99.0~101.0%


Solubility:

H2O: 10-50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.


Dosage and usage:

Intramuscular injection once per Kg body weight, livestock 10 ~ 15mg, 2 times a day, once every 3 to 5 days.


Function:

1. pharmacodynamics, the antibacterial spectrum of kanamycin is similar to streptomycin, but effect is slightly stronger. It has strong antibacterial effect on most Gram-negative bacteria, such as Escherichia coli, Proteus, Salmonella, Pasteurellamultocida, etc, and also sensitive to Staphylococcus aureus and Mycobacterium tuberculosis. Pseudomonas aeruginosa, Gram-positive bacteria (except for Staphylococcus aureus), Rickettsia, anaerobic bacteria and fungi resistant to kanamycin. Sensitive bacteria is easy to have resistance to kanamycin.

2. pharmacokinetics, the oral absorption is rare, most are excreted together with feces in prototype. Intramuscular injection is rapidly absorbed, about 0.5 to 1.5 hours to reach the peak of blood medicine, widely distributed in pleural effusion, ascites and solid organ, but it rarely penetrates saliva, bronchial secretions and normal cerebrospinal fluid. During the Meningitis, drug concentrations in cerebrospinal fluid can be increased by about 1 times. The concentration is very low in bile and feces. It is mainly excreted by glomerular filtration. 


Package: 25 kg/drum


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