Scientific Use of Antibiotics Drug(I)

- Jul 02, 2018 -

In the breeding of livestock and poultry, antibiotics are a kind of medicinal drugs with high frequency of use, but there are also cases of misuse and abuse of antibiotics. This will not only raise the cost of raising the animals, but also cause some health risks to livestock and poultry if they are used improperly. Therefore, the scientific utilization of antibiotics is the basis for guaranteeing the safe production of livestock and poultry. The editors of the current pig price network list the following points of scientific application of antibiotics in livestock and poultry breeding for reference:


First, in combination with reality, the use of drugs should be targeted. The owners and professional technicians engaged in the production and operation of livestock and poultry must be aware of the common and frequently occurring diseases of the animals in this region and their own units. According to the epidemiological data they have mastered, the laboratory pathogens should be used in diagnosis and testing, and the drug sensitivity test should be conducted. (Based on in vitro susceptibility testing and in vitro drug susceptibility testing, respectively), choose pathogens with high sensitivity (preferred drugs) or moderately sensitive (secondary drugs) antibiotics as feed additives in order to achieve prevention and promotion of growth.


Second, the dose is appropriate, and the mixing strives for uniformity. After selecting the antibiotic type, it is also necessary to determine the appropriate addition amount according to the purpose of the addition.


(A) Therapeutic dose: The therapeutic dose of various antibiotics is different, and the same kind of antibiotics are used in different animals and their use doses are not the same, such as tylosin used in pig feed to add its therapeutic amount is 100- 500 mg/kg for chickens and 300-1000 mg/kg for chickens. The therapeutic dose of antibiotics should not be added for too long. Generally, 3-7 days (one course of treatment) can be added. Then change to the preventive dose and continue to add 3-4 weeks. If the condition of the livestock is severe and the appetite is poor, antibiotics added through the feed will not achieve the desired effect. In this case, a drinking water administration route may be adopted, and the dosage should be 1/2 of the amount of feed added.


(B) Prevention dose: The purpose of adding antibiotics to feed is mainly to prevent the occurrence of a certain disease, and it usually takes a long time to add. Therefore, it is necessary to strictly control the amount of additives so as to avoid overdose and toxic drugs and unnecessary drugs. waste. The prophylactic dose is usually 1/4-1/2 of the therapeutic dose. Overuse is strictly prohibited.


(C) To promote the growth dose: antibiotics for livestock and poultry growth dose is much smaller than the therapeutic dose, usually 1/10-1/5 of the therapeutic dose. Effective dosages for different types of livestock and different types of feed are approximately 5-100 mg/kg. Generally speaking, the amount of chicks in the feed is very small, and the growth period of the pig is larger than that of the later growth period. It is worth noting that some kinds of antibiotics are effective in promoting the growth of livestock and poultry, but the simultaneous addition of two different antibiotics does not necessarily play a positive additive role. On the contrary, it is possible to produce antagonism and thus to obtain a negative additive effect. Therefore, the use of antibiotics as an additive must also consider the issue of incompatibility.


(D) Mixing evenly: The proportion of antibiotics added to the feed is extremely small. If the mixing is not uniform, it will cause drug poisoning or accident prevention. Therefore, when the drug is added, the weight must be accurately calculated and weighed, and the operation is performed according to the principle of "multiple dilution, equal increment". That is, the drug is first diluted with a small amount of carrier, and the mixture is gradually increased by equal amounts and gradually increased. If conditions are met, a 4% premixed feed may be prepared first and then mixed with the full-priced feed. The mixing time is specified for each mixing.

 

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