The Introduction of Nitenpyram

- Feb 27, 2018 -

1. Product Introduction:

Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the central nervous system of insects, causing rapid death.


It has been used orally in dogs, cats and some wildlife species for over 10 years. After ingestion, it begins killing adult fleas within 30 minutes, and effects continue for up to 48 hours. Nitenpyram is safe to use on puppies and kittens as young as four weeks old if they weigh at least 2 pounds (0.91 kg). Panting and excitement, as well as other symptoms, have been noted in cats and dogs within 2 hours of administration. In heavily infested animals, it can cause extreme itching as the fleas die. There is no known antidote for nitenpyram poisoning.


Though nitenpyram is used to kill adult fleas quickly on an infested animal, it does not kill insect eggs and has no long-term activity. Thus, it is not effective as a long-term flea preventative; however, it can be repeatedly applied over the course of several days to eradicate a single instance of infestation. Nitenpyram can be combined with a longer-term flea preventative like fipronil or lufenuron to prevent reinfestation.

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2. Uses

Nitenpyram is used for the treatment of flea infestations on dogs, puppies, cats, and kittens. It starts killing adult fleas that are on the pet within 30 minutes, but its effectiveness only lasts 24 hours. It will be very useful in certain circumstances such as prior to surgery, boarding, or grooming.It will also be useful to use before returning from shows, trials, dog parks, or other areas where your pet may be exposed to fleas.

3. Dose and Administration

Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian. Approximately 90% of adult fleas are killed within 4 hours for dogs and 6 hours for cats.If you miss a dose, or are unsure of whether the pet swallowed the pill, it is safe to give a second pill. This medication should only be given to the pet for whom it was prescribed.

4. Possible Side Effects

Pets may scratch as the fleas are dying.This is a reaction to the flea and not themedication. It is temporary.Consult your veterinarian if you notice any of the above side effects. If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately

5. Drug, Food, and Test Interactions

Consult your veterinarian before using nitenpyram with any other medications, including vitamins and supplements, since interactions may occur.Nitenpyram in the form of Capstar may beused together with other products,including heartworm preventives,corticosteroids, antibiotics, vaccines, dewormingmedications, shampoos, and other flea products.No known drug or food interactions.

6. Precautions

Not for use in animals hypersensitive(allergic) to nitenpyram.Safe to use in pregnant or lactating animals (female animals nursing their young).Do not use in puppies or kittens less than 4weeks of age.Do not use in animals less than 2 pounds.

Protection against ticks and mites has not been shown.Nitenpyram in the form of Capstar is out of the pet's system within 24 hours. The medication would have to be given every day for ongoing control. Continued control can also be accomplished by using longerlasting flea control products after the administration of nitenpyram.

Nitenpyram does not have an effect on fleas in the pet's environment. Immature fleas in and around the home will continue to develop into adults that can reinfest your pet. You may need to treat your pet or the environment with other flea control

products.Treat all infested pets in the household.Fleas can reproduce on untreated pets and allow infestations to persist.Consult with your veterinarian regarding physical examinations and laboratory testing necessary prior to and during treatment with nitenpyram.

7. Storage

Store at room temperature (59-86°F) in a

tight, light resistant, childproof container.


Contact:Sally Xu

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