Iprodione Introduction

- Apr 12, 2018 -

1, Product Introduction

Iprodione is a broad spectrum contact fungicide used to prevent the germination of fungal spores on a number of crops as well as amenity turf. Iprodione is a synthetic compound from the chemical family Dicarboximide and was first manufactured in the 1990s.

2, Application

Iprodion is used on crops affected by Botrytis bunch rot, Brown rot, Sclerotinia and other fungal diseases in plants. It is currently applied in a variety of crops: fruit, vegetables, ornamental trees and scrubs and on lawns. It is a contact fungicide that inhibits the germination of fungal spores and it blocks the growth of the fungal mycelium.

It has been marketed under the brand name "Rovral" and "Chipco green" (both brands of Bayer CropScience). This chemical was developed originally by Rhône-Poulenc Agrochimie (later Aventis CropScience and in 2002 acquired by Bayer). As of 2004 there were no composition patents on iprodione.

DevGen discovered that iprodione kills nematodes and filed for patent protection for those uses. Iprodione was approved in the Turkish market under the brandname Devguard for use on tomatoes and cucumbers in 2009, was approved in Europe in 2010, and was approved in the US as Enclosure for use in commercial peanut production in May 2010.

3, Mode of Action

Iprodione exhibits more activity on mycelial growth than spore

germination. The studies, referenced below, concerning the effect of

Iprodione on fungi, suggest:

Q no direct effect on energy production or respiration

Q no effect on cell permeability

Q no effect on DNA synthesis

Q an apparent, undefined effect on nuclear division

Reilly, C.C. and Lamoureux, G.L. 1981. The effects of the fungicide,

Iprodione, on-the mycelium of Sclerotinia sclerotiorum. Phytopathology


Georgopoulos, S.G., Sarris, M., and Ziogos, B.N. 1979. Mitotic

instability in Aspergillus nidulans caused by the fungicide iprodione,

procymidone and vinclozolin. Pest. Sci. 10:389-392.

Pappas, A.C. and Fisher, D.J. 1979. A comparison of the mechanisms of

action of vinclozolin, procymidone, iprodione and prochloroz against

Botrytis cinerea. Pest. Sci. 10:239-246.

4, Foliar Application

- Alternaria zinniae (Alternaria leaf blight)

- Ascochyta chrysanthemi (Ray blight)

- Botrytis spp. (Botrytis blight)

- Botrytis tulipae (Tulip fire)

- Drechslera iridis (Ink spot)

 Drench application

 - Rhizoctonia spp. (Rhizoctonia)

 See label for plant species

 Crucifer crops --

 - For crucifers grown for seed only; special local need registration

(24C) in Washington and Oregon.

 - Diseases: Alternaria spp. (Alternaria leaf and pod blight)

Sclerotinia spp. (Sclerotinia white rot)

5,Toxicity Data

Acute oral LD50 -Qrat 4,400 mg/kg > 10,000 mg/kg

Acute dermal LD50 -Qrabbit > 5,000 mg/kg > 5,000 mg/kg

Acute inhalation LC50 -Qrat > 3.29 g/m3 > 1.96 g/m3

Dermal irritation -Qrabbit non-irritant moderate irritant

Eye irritationQwashed -Qrabbit non-irritant mild transient irritant

Eye irritationQunwashed. mild transient mild transient irritant

Dermal sensitization -Qguinea pig non-sensitizer



Target Pets 




Botrytis cinerea



Apple tree

Alternaria leaf spot 

1000-2000times solution


Botrytis cinerea

75-1000times solution


Contact:Sally Xu  Email:pgr@pandustry.com

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