A Wonderful Usage of Amoxicillin

- Sep 23, 2018 -

The impact of pig disease on profits in pig production is enormous and often has a greater impact when clinical outbreaks occur. Early infection can have a negative impact on the pig's weaning weight and body weight at the end of the nursery. In addition, light-weight pigs are prone to disease in the later stages of farming. Some important pathogens in the key stages of pig production (birth and childbirth) are: Staphylococcus aureus, Streptococcus, Haemophilus parasuis, Pasteurella multocida, and the like.

Referring to these diseases, one of the most commonly used drugs in pig farms is amoxicillin. Amoxicillin in the production of pigs can be mixed with muscles and drinkable water. It has a large amount of use, small side effects, good effect and low price. It is deeply loved by the majority of pig farmers. However, we also found that the pig farms were used improperly in the first-line farms. Today, the usage of amoxicillin is summarized as follows. I believe it will help our pig production.

Amoxicillin is often used in the following aspects:

1. Streptococcus suis, Pasteurella and Haemophilus parasuis, and swine staphylococcal disease (amoxicillin + dexamethasone intramuscular injection) have obvious early infection effects.

2, the treatment of piglets yellow and white, pig erysipelas.

3, for sow systemic infection, postpartum anti-inflammatory.


Amoxicillin powder mix calculation

Assume that amoxicillin oral dose of 6 mg / kg body weight, pig weight 50 kg, daily feed intake of 3 kg, then: amoxicillin dosage = 6X50 = 300 mg mixed feed ratio = 300 mg / 3 kg = 100ppm. Therefore 100 grams of pure amoxicillin is added per ton of feed. At present, the amoxicillin preparation is generally 10% powder, and 1 kg of amoxicillin should be used per ton of feed to prevent general bacterial diseases. This is also the recommended dose for many veterinary drugs. The above calculation is the calculation of the amount of growth pigs, and it is best for the sows to be adjusted to 2-3 kg/ton.


10% amoxicillin: 1 kg / ton of feed is enough?

In fact, the farm uses this dose only to prevent disease, and the actual treatment dose is often greater. Because of the concern about drug resistance (as it is), amoxicillin is relatively inexpensive and safe, so adding 10% amoxicillin to 2-3 kg/ton of feed is more effective in disease control.


Here we introduce the difference between the administration of amoxicillin and the administration of drinking water, which is convenient for pig friends and friends to operate.

Mixing treatment

There are two main advantages to adding amoxicillin to the feed.

1. Less labor available to treat a large number of pigs. The use of medications for large groups of animals is very time consuming, and mixing in the feed is a very suitable method.

2. If a treatment lasts for a few days, adding the drug to the feed will reduce the probability of missing some pigs.

However, there are some disadvantages to the mixing treatment:

1. Time of action. Until all animals receive medical treatment, it may take several days. When the disease breaks out, the drug-added feed begins to be booked and sent to the farm. Finally, the tank must be empty before it can be administered.

2. Feed intake. The health status of pigs will affect feed intake, and a certain percentage of pigs may not have enough feed to get enough drug dose.

3. Manufacturing issues. Although there are different products on the market, the stability of amoxicillin molecules is affected by feed granulation. Also, premix segregation often occurs when the feed is mixed, resulting in different doses of the drug in the same batch of feed.

4. The risk of intestinal micro-ecological imbalance. Intestinal dysbiosis may occur when oral amoxicillin (or other antibiotics) is administered, resulting in impaired intestinal health in piglets.


Drinking water use

Some of the advantages of drinking water use are similar to the use of the mix:

1. Treat a large number of pigs. Drinking water treatment can treat a large number of pigs at one time with less labor, but pay attention to timely and more precise medication.

2. Targeted treatment. Targeted treatment can be carried out in units of a pig house or even in different fences in the same house. In addition, the treatment time can be carried out as needed, unlike the mixing of drugs, the animal medication period continues until the tank is empty.

3. Follow-up treatment. Amoxicillin is a very effective follow-up treatment in water, and it is especially important when the disease breaks out. Timely therapeutic dose (using the injected dose) dissolved in water can maintain the concentration of the drug in the blood of the pig at a good level and can last for several days.


At the same time, there are some disadvantages to drinking water, including:

1. The consistency of dose and treatment. In general, drinking water is not as good as the uniformity of the mixture, but it can be improved by improving equipment and training.

2. Low pH. Some farms have low water sources or use acidifiers. The solubility of amoxicillin in acidic water is affected and, according to one study, it reacts with citric acid to form a white precipitate or crystallize.

3. Drinking water. The health of pigs also affects the amount of water consumed. In addition, there is evidence that diarrhea caused by E. coli on the first day of drinking water reduces the absorption of amoxicillin.


Although amoxicillin is a good medicine, it still needs to be paid attention to when using it. It is best to choose the different methods according to the different conditions of pigs to exert the efficacy of amoxicillin. The administration of amoxicillin in drinking water is generally not more than 3 hours, and the administration time may be too long to cause the efficacy to be lowered or invalid!





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